We explore the interplay between bacteriophages, phage resistance mechanisms, ecology, and evolution. We aim to apply insights from our work to assist in the fight against antibiotic resistance in bacterial pathogens. Research projects include:
- Experimental evolution of anti-phage defense systems.
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Investigate the mechanisms of how key cellular processes, such as transcription, modulate bacterial anti-phage defense systems.
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Genetic trade-offs of phage resistance mechanisms.
- Phage infection in poly-microbial communities.